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For more information about possible Unintended effects which could have an effect on your driving see area four of the leaflet.If you obtain any Unwanted side effects, talk with your doctor or pharmacist. This contains any possible Unwanted effects not mentioned With this leaflet.If you're taking this drug with tramadol, your doctor might check yo

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Itrakonazol, ketokonazol i u manjoj meri flukonazol i vorikonazol su snažni inhibitori izoenzima CYP3A4 citohroma P450 i mogu povećati koncentraciju benzodiazepina u plazmi.Fenobarbital uzet istovremeno može dovesti do aditivnog efekta na CNS. Povećan je rizik od sedacije i respiratorne depresije. Poznato je da fenobarbital indukuje CYP3A4 enzi

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